Who we are: The Moellering Lab is a multi-disciplinary group of scientists with training in chemistry, biochemistry, cell biology and mass spectrometry. We are uniquely situated in both the Department of Chemistry and the Institute for Genomics and Systems Biology at the University of Chicago – thus figuratively and physically bridging the physical and biological sciences.
What we do: Research in the Moellering Lab lies at the interface of chemistry and biology, with an eye towards understanding and intervening in human disease. By integrating chemical synthesis, cell biology and mass spectrometry platforms, our research aims to identify novel biological mechanisms underlying diseases such as diabetes and cancer, and to subsequently develop innovative diagnostic and therapeutic modalities to impact these disorders. We are specifically interested in developing new chemical tools and technologies to study complexity and dynamics in the proteome, thus enabling targeted manipulation of protein targets and the pathways they govern.
Lab News and Announcements
Open Positions: The Moellering Lab is seeking interdisciplinary researchers at the postdoctoral, graduate and undergraduate level. Check out our recent publications, as well as active areas of research, and contact us about current opportunities in the lab.
News!
September, 2025: Ray has been awarded an Allstars Grant from the The V Foundation for Cancer Research to develop new inhibitors of “undruggable” oncoproteins in childhood cancers! Read more about the V Foundation here and our work on Undruggable targets here.